AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine
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منابع مشابه
AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine
Activation-induced cytidine deaminase (AID) was originally identified as an inducer of somatic hypermutation (SHM) and class switch recombination (CSR) in immunoglobulin genes. However, AID can also cause mutations in host genes and contribute to cancer progression and drug resistance. In this study, molecular docking showed the interaction of free 5-aza-CdR and Zebularine (Zeb) with AID. Howev...
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15 صفحه اولDelivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides.
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2013
ISSN: 1949-2553
DOI: 10.18632/oncotarget.1319